Wall Street stocks fell again Thursday, while the major indexes were on track for a weekly gain following a strong two-day run earlier this week.

The S&P 500 dropped 0.8%. Nearly three-fourths of the equities in the index ended in the red, with retailers, banks and industrial companies among the biggest weights. The Dow Jones Industrial Average declined 0.3%, while the Nasdaq Composite dropped 0.6%. Small-cap stocks fell more than the broader market, with the Russell 2000 index down 1.2%.

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Treasury yields have continued to rise to multiyear highs, contributing to higher mortgage and other borrowing rates. The yield on the 10-year Treasury climbed to 4.23% from 4.14% late Wednesday and is at its highest level in 14 years. The yield on the two-year Treasury, which tends to track expectations for future Federal Reserve action, rose to 4.61% from 4.56%.

IBM rose 4.7% after its third-quarter earnings and revenue topped analysts’ forecasts. AT&T jumped 7.7% after also reporting strong results.

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Tesla fell 6.6% after saying it will miss its target for vehicle deliveries this year. Union Pacific dropped 6.8% after the railroad operator predicted slower growth, suggesting that the economy may be slowing down. Rival CSX fell 3%. American Airlines fell 3.8% after reporting its latest results.

Allstate slumped 12.9% after giving investors a disappointing financial update.

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All told, the S&P 500 fell 29.38 points to 3,665.78. The Dow lost 90.22 points to close at 30,333.59. The Nasdaq dropped 65.66 points to 10,614.84. The Russell 2000 fell 21.36 points, to 1,704.39.

Markets in Europe closed higher. British Prime Minister Liz Truss resigned following financial market turmoil caused by multiple policy U-turns.

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The sharp rate increases have pushed mortgage rates up to 15-year highs. Mortgage buyer Freddie Mac reported Thursday that the average on the key 30-year rate ticked up this week to 6.94% from 6.92% last week. Last year at this time, the rate was 3.09%.