Although New Orleans will be happy with the resilient show they put up to beat Tampa Bay Buccaneers 36-27, the Saints ended the night on a bitter-sweet note as their first-choice quarterback Jameis Winston was injured during the game.

Winston was carted to the locker room with a left knee injury after Buccaneers linebacker Devin White pulled him down on a scramble in the second quarter of the game. The 27-year-old was immediately taken to the medical tent before a cart took him away. White was flagged for a horse-collar tackle. 

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Trevor Siemian replaced Winston off the bench. The 29-year-old took over and threw for 159 yards and a score on 16 of 29 passing with no interceptions, leading the Saints on five scoring drives with two touchdowns and three field goals.

Talking about Winston’s injury, Saints coach Sean Payton said, “I think it’s significant.”

“He felt something and is on crutches right now. … When he got up and then had to go back down, you were a little concerned.”

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Meanwhile, the Buccaneers lost tight end Rob Gronkowski in the first half against the Saints. Gronkowski left due to back spasms in his first game back after missing four games with injured ribs. In other games, Colts wide receiver T.Y. Hilton also got hurt in his return to the lineup. He was diagnosed with a concussion after hitting his head hard on the ground trying to make a catch during an overtime loss to Tennessee. Indianapolis also lost safety Khari Willis (calf) during the game.

Other injuries in Week 8 include 49ers safety Jimmie Ward (quad), Bears safety Eddie Jackson (hamstring), Bears running back Damien Williams (knee), Rams rookie wide receiver TuTu Atwell (shoulder), Eagles wideout Jalen Reagor (ankle) , Washington center Chase Roullier (ankle), Broncos cornerback Bryce Callahan (leg), Broncos left tackle Garett Bolles (leg), andChargers cornerback Michael Davis (hamstring).

With inputs from the Associated Press