San Francisco 49ers' QB Trey Lance. (Photo credit: AP)

  • San Francisco 49ers running back Raheem Mostert was ruled out because of a knee injury
  • After Mostert’s injury, the 49ers now only have two other active running backs as options
  • Linebacker Dre Greenlaw is dealing with a groin injury

.San Francisco, CA, USA
Trey Lance was picked by the 49ers in the 2021 draft.(Photo Credit: Twitter/@treylance)

  • Trey Lance made his debut for San Francisco 49ers on Sunday 
  • His first-career pass went for a touchdown against Detriot Lions
  • Coach Kyle Shanahan decided not to start Lance at his preferred position