India’s first 3D printed Cornea has been recently developed by a research team based in which city?
Delhi
Hyderabad
Pune
Ahmedabad
Answer: Hyderabad
Earlier this month, a team of clinicians and scientists from Hyderabad developed s 3D-printed artificial cornea and transplanted it into a rabbit’s eye.
Researchers from the Indian Institute of Technology (IIT) Hyderabad, the Centre for Cellular and Molecular Biology (CCMB), and the LV Prasad Eye Institute (LVPEI), Hyderabad, worked together to create the 3D-printed cornea from human donor corneal tissue that would have otherwise been discarded for failing to meet optical standards for clinical transportation.
“With recent advancements in regenerative medicine and tissue engineering, the researchers from LVPEI, IIT-H and CCMB used decellularised corneal tissue matrix and stem cells derived from the human eye to develop a unique biomimetic hydrogel (patent pending) that was used as the background material for the 3D-printed cornea. Because the 3D-printed cornea is composed of materials deriving from human corneal tissue, it is biocompatible, natural, and free of animal residues. In addition, since the tissue used for this technology is derived from donor corneas that do not meet the optical standards for clinical transplantation, this method also finds unique use for the donated corneas that would otherwise be discarded,” said a press note.
Dr Sayan Basu and Dr Vivek Singh, who are the lead researchers from L V Prasad Eye Institute, called it ground-breaking. They said it was a disruptive innovation in treating diseases like corneal scarring (where the cornea becomes opaque) or Keratoconus (where the cornea gradually becomes thin with time).
“It is a made-in-India product by an Indian clinician-scientist team and the first 3-D printed human cornea that is optically and physically suitable for transplantation. The bio-ink used to make this 3D printed cornea can be sight-saving for army personnel at the site of injury to seal the corneal perforation and prevent infection during war-related injuries or in a remote area with no tertiary eye care facility,” they said.
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